Ladino, otherwise called Judeo-Spanish, is the language spoken and written by Jews of Spanish origin, called Sephardic Jews. Estimates vary as to how widely spoken this language is; most scholars quote figures between 160,000 and 300,000. In printed publications, Ladino was almost always written in the Rashi style of the Hebrew script, or in an adapted Hebrew script called Solitreo. In the later years leading to WWII, it was also sometimes written in the modern block style of Hebrew. Since the late 20th century, Ladino has generally been written in the Latin alphabet, using a phonetic transcription system.

The letters used for the Solitreo script are all taken from the Hebrew script; no extra letters have been added, despite the Ladino language containing a number of non-Semitic sounds. However, whereas in Hebrew multiple letters may be used for writing the same sound - vet ב and vav ו both represent [v], kaph כ and qoph ק both represent [k], etc. - in Solitreo, one Ladino sound is generally represented consistently by one letter; vet is used but not vav, qoph but not kaph, samech but not sin, and so on. Those letters which are not used for writing Ladino sounds tend only to be used when writing words of Semitic origin (or occasionally, words of other origins).  This chart gives a clear overview comparison of the letters used for various sounds in Hebrew and Solitreo writing.

Unlike traditional Hebrew writing, when writing in Solitreo all vowels are represented. The Hebrew niqqud system of marking vowels using diacritics is not used; rather, the letters vav ו, yud י, and aleph א are used for representing u/o, i/e, and a, respectively. The three vowel letters are combined for writing diphthongs. Words which start with a vowel are written with a silent aleph prefix.

The rafe diacritic, obsolete in modern written Hebrew, is used in Solitreo writing to produce non-Semitic sounds. Gimel ג, which represents [g], when written with a rafe diacritic represents [dʒ] or [tʃ].